How I treat relapsed or refractory ALL

At the 2023 Know ALL Community Meeting, Dr. Nicola Gökbuget, University Hospital Frankfurt, Frankfurt, DE, delivers an expert-led session on the topic of how I treat relapsed or refractory ALL.

Gökbuget begins by providing an overview of adult ALL, focusing on how ALL is measured and how relapsed/refractory ALL is defined. She then discusses the steps after detection of relapse and elaborates on the factors that impact treatment decisions and goals. Speaking on relapsed/refractory ALL, Gökbuget contrasts the primary therapeutic approaches between T-ALL and Philadelphia chromosome-positive/-negative B-ALL. She then outlines several specific targeted approaches using real-world data. Before closing, Gökbuget also evaluates the impact of CAR T-cell therapy in adult ALL.